Sillamäe linnas tegutsevad paljud suured ettevõtted. Suuremad nendest on:

 

• AS Sillamäe Sadam
• NPM SILMET AS
• AS Alexela Sillamäe
• AS Sillamäe SEJ   
• AS Norwes Metall
• AS Westaqua-Distribution (Aquaphor)